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MKP1 mediates resistance to therapy in HER2-positive breast tumors
Mitogen-activated protein kinase phosphatase 1 (MKP1 or DUSP1) is an antiapoptotic phosphatase that is overexpressed in many cancers, including breast cancer. MKP1 expression is inducible in radiation-treated breast cancer cells, and correlates with human epidermal growth factor receptor 2 (ERBB2, H...
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| 發表在: | Mol Cell Oncol |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905363/ https://ncbi.nlm.nih.gov/pubmed/27308517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2014.997518 |
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