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The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents

Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Development of resistance to chemotherapeutic agents is a major hurdle in the effective treatment of patients with AML. The quinazolinone derivative erastin was originally identified in a screen for small molecules that exhi...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Yu, Yan, Xie, Yangchun, Cao, Lizhi, Yang, Liangchun, Yang, Minghua, Lotze, Michael T., Zeh, Herbert J., Kang, Rui, Tang, Daolin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905356/
https://ncbi.nlm.nih.gov/pubmed/27308510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1054549
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