The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents

Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Development of resistance to chemotherapeutic agents is a major hurdle in the effective treatment of patients with AML. The quinazolinone derivative erastin was originally identified in a screen for small molecules that exhi...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Yu, Yan, Xie, Yangchun, Cao, Lizhi, Yang, Liangchun, Yang, Minghua, Lotze, Michael T., Zeh, Herbert J., Kang, Rui, Tang, Daolin
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905356/
https://ncbi.nlm.nih.gov/pubmed/27308510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1054549
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