The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents

Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Development of resistance to chemotherapeutic agents is a major hurdle in the effective treatment of patients with AML. The quinazolinone derivative erastin was originally identified in a screen for small molecules that exhi...

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Publicado en:Mol Cell Oncol
Autores principales: Yu, Yan, Xie, Yangchun, Cao, Lizhi, Yang, Liangchun, Yang, Minghua, Lotze, Michael T., Zeh, Herbert J., Kang, Rui, Tang, Daolin
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905356/
https://ncbi.nlm.nih.gov/pubmed/27308510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1054549
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