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Induction of pyroptosis in colon cancer cells by LXRβ

Liver X receptors (LXRs) have been proposed to have some anticancer properties. We recently identified a new non-genomic role of LXRβ in colon cancer cells. Under LXR agonist treatment, LXRβ induces pyroptosis of these cells in vitro and in vivo, raising the possibility of targeting this isoform in...

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Pubblicato in:Mol Cell Oncol
Autori principali: Rébé, Cédric, Derangère, Valentin, Ghiringhelli, François
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905240/
https://ncbi.nlm.nih.gov/pubmed/27308405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.970094
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