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Molecular mechanisms involved in initiation of the DNA damage response

DNA is subject to a wide variety of damage. In order to maintain genomic integrity, cells must respond to this damage by activating repair and cell cycle checkpoint pathways. The initiating events in the DNA damage response entail recognition of the lesion and the assembly of DNA damage response com...

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Bibliografiske detaljer
Udgivet i:Mol Cell Oncol
Main Authors: Barnum, Kevin J, O’Connell, Matthew J
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905235/
https://ncbi.nlm.nih.gov/pubmed/27308403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.970065
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