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Telomere uncapping at the crossroad between cell cycle arrest and carcinogenesis
Telomeres are nucleoprotein complexes that protect the natural ends of chromosomes from fusion and degradation and prevent them eliciting a checkpoint response. This protective function, which is called telomere capping, is largely mediated by telomere-binding proteins that suppress checkpoint activ...
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Publicado no: | Mol Cell Oncol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905175/ https://ncbi.nlm.nih.gov/pubmed/27308311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mco.29901 |
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