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Telomere uncapping at the crossroad between cell cycle arrest and carcinogenesis

Telomeres are nucleoprotein complexes that protect the natural ends of chromosomes from fusion and degradation and prevent them eliciting a checkpoint response. This protective function, which is called telomere capping, is largely mediated by telomere-binding proteins that suppress checkpoint activ...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Gobbini, Elisa, Trovesi, Camilla, Cassani, Corinne, Longhese, Maria Pia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905175/
https://ncbi.nlm.nih.gov/pubmed/27308311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mco.29901
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