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G(1)/S and G(2)/M Cyclin-Dependent Kinase Activities Commit Cells to Death in the Absence of the S-Phase Checkpoint

The Mec1 and Rad53 protein kinases are essential for budding yeast cell viability and are also required to activate the S-phase checkpoint, which supports DNA replication under stress conditions. Whether these two functions are related to each other remains to be determined, and the nature of the re...

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Sonraí Bibleagrafaíochta
Main Authors: Manfrini, Nicola, Gobbini, Elisa, Baldo, Veronica, Trovesi, Camilla, Lucchini, Giovanna, Longhese, Maria Pia
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510536/
https://ncbi.nlm.nih.gov/pubmed/23045388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00956-12
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