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Targeting the sumoylation pathway in cancer stem cells

Cancer stem cells (CSCs) represent a subset of tumor cells with tumor-initiating potential. We recently demonstrated that inhibition of the sumoylation pathway cleared the CSC population and repressed the outgrowth of basal breast cancer xenografts. Targeting the sumoylation pathway offers a novel t...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Bogachek, Maria V, De Andrade, James P, Weigel, Ronald J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905063/
https://ncbi.nlm.nih.gov/pubmed/27308355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.964624
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