Sumoylation Pathway Is Required to Maintain the Basal Breast Cancer Subtype

The TFAP2C/AP-2γ transcription factor regulates luminal breast cancer genes and loss of TFAP2C induces epithelial-mesenchymal transition. By contrast, the highly homologous family member, TFAP2A, lacks transcriptional activity at luminal gene promoters. A detailed structure-function analysis identif...

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Detalhes bibliográficos
Main Authors: Bogachek, Maria V., Chen, Yizhen, Kulak, Mikhail V., Woodfield, George W., Cyr, Anthony R., Park, Jung Min, Spanheimer, Philip M., Li, Yingyue, Li, Tiandao, Weigel, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096794/
https://ncbi.nlm.nih.gov/pubmed/24835590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2014.04.008
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