High TFAP2C/low CD44 expression is associated with an increased rate of pathologic complete response following neoadjuvant chemotherapy in breast cancer

BACKGROUND: In luminal breast cancer cell lines, TFAP2C regulates expression of key genes in the estrogen receptor–associated cluster and represses basal-associated genes including CD44. We examined the effect of TFAP2C overexpression in a basal cell line and characterized the expression of TFAP2C a...

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Bibliografiske detaljer
Main Authors: Spanheimer, Philip M., Askeland, Ryan W., Kulak, Mikhail V., Wu, Tong, Weigel, Ronald J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820425/
https://ncbi.nlm.nih.gov/pubmed/23764310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2013.04.042
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