Cargando...

Redox-sensitive TP53INP1 SUMOylation as an oxidative stress sensor to activate TP53

Oxidative stress-induced sumoylation of TP53INP1 (tumor protein p53-induced nuclear protein 1) is essential to enhance the TP53 response. Sumoylation of TP53INP1 on the K113 residue, which is mediated by protein inhibitor of activated STAT 3 (PIAS3) and chromobox homolog 4 (CBX4) and removed by SUMO...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Mol Cell Oncol
Main Authors: Bonacci, Thomas, Peuget, Sylvain, Soubeyran, Philippe, Iovanna, Juan, Dusetti, Nelson J
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905059/
https://ncbi.nlm.nih.gov/pubmed/27308354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.964044
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!