Oxidative stress-induced p53 activity is enhanced by a redox-sensitive TP53INP1 SUMOylation

Tumor Protein p53-Induced Nuclear Protein 1 (TP53INP1) is a tumor suppressor that modulates the p53 response to stress. TP53INP1 is one of the key mediators of p53 antioxidant function by promoting the p53 transcriptional activity on its target genes. TP53INP1 expression is deregulated in many types...

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Hauptverfasser: Peuget, S, Bonacci, T, Soubeyran, P, Iovanna, J, Dusetti, N J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207477/
https://ncbi.nlm.nih.gov/pubmed/24608790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.28
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