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TP53INP1, a tumor suppressor, interacts with LC3 and ATG8-family proteins through the LC3-interacting region (LIR) and promotes autophagy-dependent cell death

TP53INP1 (tumor protein 53-induced nuclear protein 1) is a tumor suppressor, whose expression is downregulated in cancers from different organs. It was described as a p53 target gene involved in cell death, cell-cycle arrest and cellular migration. In this work, we show that TP53INP1 is also able to...

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Autores principales: Seillier, M, Peuget, S, Gayet, O, Gauthier, C, N'Guessan, P, Monte, M, Carrier, A, Iovanna, J L, Dusetti, N J
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422476/
https://ncbi.nlm.nih.gov/pubmed/22421968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.30
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