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Discovery and validation of the antimetastatic activity of citalopram in colorectal cancer

Inverse gene expression profiling was recently shown to help drug repositioning. We showed that this approach works best for cancer and predicted novel drug candidates that may reduce metastasis in colorectal cancer. Antimetastatic activity of our predicted candidate, citalopram, was validated in an...

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Pubblicato in:Mol Cell Oncol
Autori principali: Iskar, Murat, Bork, Peer, van Noort, Vera
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904995/
https://ncbi.nlm.nih.gov/pubmed/27308430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.975080
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