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Revealing human intestinal stem cell and crypt dynamics

Stem cell and crypt dynamics in the human gut have been remarkably poorly characterized. We used random somatic mutations to trace stem cell lineages in the human intestine and coupled these data with mathematical modeling to infer the in vivo temporal dynamics of human intestinal stem cells.

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Baker, Ann-Marie, Graham, Trevor A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904973/
https://ncbi.nlm.nih.gov/pubmed/27308359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.970069
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