TRIM32 is a novel negative regulator of p53

To ensure proper function, the tumor suppressor p53 is tightly regulated through different post-translational modifications, particularly ubiquitination. Recently, TRIM32 was identified as a p53-regulated gene and an E3 ubiquitin ligase of p53. Thus, TRIM32 and p53 form a novel auto-regulatory negat...

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Bibliographic Details
Published in:Mol Cell Oncol
Main Authors: Liu, Juan, Zhu, Yu, Hu, Wenwei, Feng, Zhaohui
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904883/
https://ncbi.nlm.nih.gov/pubmed/27308422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.970951
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