ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity

The selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker 4-(N-ethyl-N-phenylamino)-1,2-dimethyl-6-(methylamino) pyrimidinium chloride (ZD7288) blocks the induction of long-term potentiation in the perforant path–CA3 region in rat hippocampus in vivo. To explore the mec...

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Publicat a:Neural Regen Res
Autors principals: Zhang, Xiao-xue, Min, Xiao-chun, Xu, Xu-lin, Zheng, Min, Guo, Lian-jun
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904469/
https://ncbi.nlm.nih.gov/pubmed/27335562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.182705
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