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CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development

Genome-wide epigenetic reprogramming is required for successful preimplantation development. Inappropriate or deficient chromatin regulation can result in defective lineage specification and loss of genomic imprinting, compromising normal development. Here we report that two members of the RNA polym...

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Vydáno v:Dev Biol
Hlavní autoři: Zhang, Kun, Haversat, Jocelyn M., Mager, Jesse
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4903072/
https://ncbi.nlm.nih.gov/pubmed/24036311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.09.005
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