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Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation

The evolutionarily conserved multifunctional polymerase-associated factor 1 (Paf1) complex (Paf1C), which is composed of at least five subunits (Paf1, Leo1, Ctr9, Cdc73, and Rtf1), plays vital roles in gene regulation and has connections to development and human diseases. Here, we report two structu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Xie, Ying, Zheng, Minying, Chu, Xinlei, Chen, Yue, Xu, Huisha, Wang, Jiawei, Zhou, Hao, Long, Jiafu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143631/
https://ncbi.nlm.nih.gov/pubmed/30228257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06237-7
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