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Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation

The evolutionarily conserved multifunctional polymerase-associated factor 1 (Paf1) complex (Paf1C), which is composed of at least five subunits (Paf1, Leo1, Ctr9, Cdc73, and Rtf1), plays vital roles in gene regulation and has connections to development and human diseases. Here, we report two structu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Xie, Ying, Zheng, Minying, Chu, Xinlei, Chen, Yue, Xu, Huisha, Wang, Jiawei, Zhou, Hao, Long, Jiafu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143631/
https://ncbi.nlm.nih.gov/pubmed/30228257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06237-7
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