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Developmental stage-specific effects of Pim-1 dysregulation on murine bone marrow B cell development
BACKGROUND: The serine threonine kinase Pim-1 has documented roles in hematopoietic progenitor and B cell precursor proliferation and survival. Pim-1 is a molecular target of the transcription factor Hoxa9. Previous studies showed that Pim-1 deficiency phenocopied the hematopoietic progenitor defect...
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| Veröffentlicht in: | BMC Immunol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4902936/ https://ncbi.nlm.nih.gov/pubmed/27287229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-016-0152-1 |
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