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Brain Aggregates: An Effective In Vitro Cell Culture System Modeling Neurodegenerative Diseases

Drug discovery for neurodegenerative diseases is particularly challenging because of the discrepancies in drug effects between in vitro and in vivo studies. These discrepancies occur in part because current cell culture systems used for drug screening have many limitations. First, few cell culture s...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Ahn, Misol, Kalume, Franck, Pitstick, Rose, Oehler, Abby, Carlson, George, DeArmond, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902861/
https://ncbi.nlm.nih.gov/pubmed/26851378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlv025
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