The Prion Disease Database: a comprehensive transcriptome resource for systems biology research in prion diseases

Prion diseases reflect conformational conversion of benign isoforms of prion protein (PrP(C)) to malignant PrP(Sc) isoforms. Networks perturbed by PrP(Sc) accumulation and their ties to pathological events are poorly understood. Time-course transcriptomic and phenotypic data in animal models are cri...

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Bibliografiske detaljer
Main Authors: Gehlenborg, Nils, Hwang, Daehee, Lee, Inyoul Y., Yoo, Hyuntae, Baxter, David, Petritis, Brianne, Pitstick, Rose, Marzolf, Bruz, DeArmond, Stephen J., Carlson, George A., Hood, Leroy
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790306/
https://ncbi.nlm.nih.gov/pubmed/20157484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/database/bap011
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