The Prion Disease Database: a comprehensive transcriptome resource for systems biology research in prion diseases

Prion diseases reflect conformational conversion of benign isoforms of prion protein (PrP(C)) to malignant PrP(Sc) isoforms. Networks perturbed by PrP(Sc) accumulation and their ties to pathological events are poorly understood. Time-course transcriptomic and phenotypic data in animal models are cri...

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Detalhes bibliográficos
Main Authors: Gehlenborg, Nils, Hwang, Daehee, Lee, Inyoul Y., Yoo, Hyuntae, Baxter, David, Petritis, Brianne, Pitstick, Rose, Marzolf, Bruz, DeArmond, Stephen J., Carlson, George A., Hood, Leroy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790306/
https://ncbi.nlm.nih.gov/pubmed/20157484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/database/bap011
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