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N(ε)-Carboxymethyl Modification of Lysine Residues in Pathogenic Prion Isoforms

The most prominent hallmark of prion diseases is prion protein conversion and the subsequent deposition of the altered prions, PrP(Sc), at the pathological sites of affected individuals, particularly in the brain. A previous study has demonstrated that the N-terminus of the pathogenic prion isoform...

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Dades bibliogràfiques
Publicat a:Mol Neurobiol
Autors principals: Choi, Yeong-Gon, Shin, Hae-Young, Kim, Jae-Il, Choi, Eun-Kyoung, Carp, Richard I., Kim, Yong-Sun
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902843/
https://ncbi.nlm.nih.gov/pubmed/25983034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9200-8
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