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N(ε)-Carboxymethyl Modification of Lysine Residues in Pathogenic Prion Isoforms

The most prominent hallmark of prion diseases is prion protein conversion and the subsequent deposition of the altered prions, PrP(Sc), at the pathological sites of affected individuals, particularly in the brain. A previous study has demonstrated that the N-terminus of the pathogenic prion isoform...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Choi, Yeong-Gon, Shin, Hae-Young, Kim, Jae-Il, Choi, Eun-Kyoung, Carp, Richard I., Kim, Yong-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902843/
https://ncbi.nlm.nih.gov/pubmed/25983034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9200-8
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