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A cross-metathesis approach to novel pantothenamide derivatives

Pantothenamides are known for their in vitro antimicrobial activity. Our group has previously reported a new stereoselective route to access derivatives modified at the geminal dimethyl moiety. This route however fails in the addition of large substituents. Here we report a new synthetic route that...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Guan, Jinming, Hachey, Matthew, Puri, Lekha, Howieson, Vanessa, Saliba, Kevin J, Auclair, Karine
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902030/
https://ncbi.nlm.nih.gov/pubmed/27340487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.95
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