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Gold-catalyzed direct alkynylation of tryptophan in peptides using TIPS-EBX

The selective functionalization of peptides containing only natural amino acids is important for the modification of biomolecules. In particular, the installation of an alkyne as a useful handle for bioconjugation is highly attractive, but the use of a carbon linker is usually required. Herein, we r...

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Bibliografske podrobnosti
izdano v:Beilstein J Org Chem
Main Authors: Tolnai, Gergely L, Brand, Jonathan P, Waser, Jerome
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902029/
https://ncbi.nlm.nih.gov/pubmed/27340466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.74
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