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One-pot gold-catalyzed synthesis of 3-silylethynyl indoles from unprotected o-alkynylanilines

The Au(III)-catalyzed cyclization of 2-alkynylanilines was combined in a one-pot procedure with the Au(I)-catalyzed C3-selective direct alkynylation of indoles using the benziodoxolone reagent TIPS-EBX to give a mild, easy and straightforward entry to 2-substituted-3-alkynylindoles. The reaction can...

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Detalhes bibliográficos
Main Authors: Brand, Jonathan P, Chevalley, Clara, Waser, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107533/
https://ncbi.nlm.nih.gov/pubmed/21647264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.7.65
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