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Secretagogin affects insulin secretion in pancreatic β-cells by regulating actin dynamics and focal adhesion
Secretagogin (SCGN), a Ca(2+)-binding protein having six EF-hands, is selectively expressed in pancreatic β-cells and neuroendocrine cells. Previous studies suggested that SCGN enhances insulin secretion by functioning as a Ca(2+)-sensor protein, but the underlying mechanism has not been elucidated....
Shranjeno v:
| izdano v: | Biochem J |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Portland Press Ltd.
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4901359/ https://ncbi.nlm.nih.gov/pubmed/27095850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160137 |
| Oznake: |
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