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Predictive modeling targets thymidylate synthase ThyX in Mycobacterium tuberculosis

There is an urgent need to identify new treatments for tuberculosis (TB), a major infectious disease caused by Mycobacterium tuberculosis (Mtb), which results in 1.5 million deaths each year. We have targeted two essential enzymes in this organism that are promising for antibacterial therapy and rep...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Djaout, Kamel, Singh, Vinayak, Boum, Yap, Katawera, Victoria, Becker, Hubert F., Bush, Natassja G., Hearnshaw, Stephen J., Pritchard, Jennifer E., Bourbon, Pauline, Madrid, Peter B., Maxwell, Anthony, Mizrahi, Valerie, Myllykallio, Hannu, Ekins, Sean
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901301/
https://ncbi.nlm.nih.gov/pubmed/27283217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27792
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