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Discovery of novel peptides targeting pro-atherogenic endothelium in disturbed flow regions -Targeted siRNA delivery to pro-atherogenic endothelium in vivo

Atherosclerosis occurs preferentially in arterial regions exposed to disturbed blood flow. Targeting these pro-atherogenic regions is a potential anti-atherogenic therapeutic approach, but it has been extremely challenging. Here, using in vivo phage display approach and the partial carotid ligation...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Chung, Jihwa, Shim, Hyunbo, Kim, Kwanchang, Lee, Duhwan, Kim, Won Jong, Kang, Dong Hoon, Kang, Sang Won, Jo, Hanjoong, Kwon, Kihwan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901192/
https://ncbi.nlm.nih.gov/pubmed/27173134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25636
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