Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting Endoplasmic Reticulum (ER) Stress Induced by Disturbed Flow

Disturbed blood flow with low-oscillatory shear stress (OSS) is a predominant atherogenic factor leading to dysfunctional endothelial cells (ECs). Recently, it was found that disturbed flow can directly induce endoplasmic reticulum (ER) stress in ECs, thereby playing a critical role in the developme...

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Bibliographic Details
Published in:Mol Cells
Main Authors: Chung, Jihwa, Kim, Kyoung Hwa, Lee, Seok Cheol, An, Shung Hyun, Kwon, Kihwan
Format: Artigo
Language:Inglês
Published: Korean Society for Molecular and Cellular Biology 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625066/
https://ncbi.nlm.nih.gov/pubmed/26442866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.0094
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