Isolation of Pancreatic Cancer Cells from a Patient-Derived Xenograft Model Allows for Practical Expansion and Preserved Heterogeneity in Culture

Commercially available, highly passaged pancreatic cancer (PC) cell lines are of limited translational value. Attempts to overcome this limitation have primarily consisted of cancer cell isolation and culture directly from human PC specimens. However, these techniques are associated with exceedingly...

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Foilsithe in:Am J Pathol
Main Authors: Pham, Kien, Delitto, Daniel, Knowlton, Andrea E., Hartlage, Emily R., Madhavan, Ricky, Gonzalo, David H., Thomas, Ryan M., Behrns, Kevin E., George, Thomas J., Hughes, Steven J., Wallet, Shannon M., Liu, Chen, Trevino, Jose G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2016
Ábhair:
Regular Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901138/
https://ncbi.nlm.nih.gov/pubmed/27102771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.02.009
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