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Wild-type opsin does not aggregate with a misfolded opsin mutant

Rhodopsin is the light receptor in photoreceptor cells that plays a central role in phototransduction and photoreceptor cell health. Mutations in rhodopsin are the leading cause of autosomal dominant retinitis pigmentosa (adRP), a retinal degenerative disease. A majority of mutations in rhodopsin ca...

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發表在:Biochim Biophys Acta
Main Authors: Gragg, Megan, Kim, Tae Gyun, Howell, Scott, Park, Paul S.-H.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900927/
https://ncbi.nlm.nih.gov/pubmed/27117643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2016.04.013
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