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Misfolded rhodopsin mutants display variable aggregation properties

The largest class of rhodopsin mutations causing autosomal dominant retinitis pigmentosa (adRP) is mutations that lead to misfolding and aggregation of the receptor. The misfolding mutants have been characterized biochemically, and categorized as either partial or complete misfolding mutants. This c...

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Bibliografiska uppgifter
I publikationen:Biochim Biophys Acta
Huvudupphovsmän: Gragg, Megan, Park, Paul S-H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066411/
https://ncbi.nlm.nih.gov/pubmed/29890221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.06.004
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