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Alcohol, TLR4-TGF-β Antagonism, and Liver Cancer

Alcohol abuse and obesity are two known risk factors for hepatocellular carcinoma (HCC) that also synergistically promote HBV/HCV-related carcinogenesis. TLR4, the PAMP for endotoxin participates in inflammatory processes such as M1 activation of hepatic macrophages in alcoholic liver disease. Howev...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Hepatol Int
Main Authors: Tsukamoto, Hidekazu, Mishra, Lopa, Machida, Keigo
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900455/
https://ncbi.nlm.nih.gov/pubmed/26201318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-013-9489-1
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