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“Second Hit” Models of Alcoholic Liver Disease

Alcoholic liver disease (ALD) is a lifestyle disease with its pathogenesis and individual predisposition governed by gene–environment interactions. Based on the “second hit” or “multiple hits” hypothesis, patients are predisposed to progressive ALD when a magic combination of gene and environmental...

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Bibliographic Details
Main Authors: Tsukamoto, Hidekazu, Machida, Keigo, Dynnyk, Alla, Mkrtchyan, Hasmik
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197797/
https://ncbi.nlm.nih.gov/pubmed/19387917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0029-1214373
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