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Mammalian α-1,6-Fucosyltransferase (FUT8) Is the Sole Enzyme Responsible for the N-Acetylglucosaminyltransferase I-independent Core Fucosylation of High-mannose N-Glycans

Understanding the biosynthetic pathway of protein glycosylation in various expression cell lines is important for controlling and modulating the glycosylation profiles of recombinant glycoproteins. We found that expression of erythropoietin (EPO) in a HEK293S N-acetylglucosaminyltransferase I (GnT I...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yang, Qiang, Wang, Lai-Xi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900256/
https://ncbi.nlm.nih.gov/pubmed/27008861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.720789
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