Generation of a Mutant Mucor hiemalis Endoglycosidase That Acts on Core-fucosylated N-Glycans

Endo-β-N-acetylglucosaminidase M (Endo-M), an endoglycosidase from the fungus Mucor hiemalis, is a useful tool for chemoenzymatic synthesis of glycoconjugates, including glycoprotein-based therapeutics having a precisely defined glycoform, by virtue of its transglycosylation activity. Although Endo-...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Katoh, Toshihiko, Katayama, Takane, Tomabechi, Yusuke, Nishikawa, Yoshihide, Kumada, Jyunichi, Matsuzaki, Yuji, Yamamoto, Kenji
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087746/
https://ncbi.nlm.nih.gov/pubmed/27629418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.737395
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