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Mammalian α-1,6-Fucosyltransferase (FUT8) Is the Sole Enzyme Responsible for the N-Acetylglucosaminyltransferase I-independent Core Fucosylation of High-mannose N-Glycans

Understanding the biosynthetic pathway of protein glycosylation in various expression cell lines is important for controlling and modulating the glycosylation profiles of recombinant glycoproteins. We found that expression of erythropoietin (EPO) in a HEK293S N-acetylglucosaminyltransferase I (GnT I...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Yang, Qiang, Wang, Lai-Xi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900256/
https://ncbi.nlm.nih.gov/pubmed/27008861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.720789
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