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Mammalian α-1,6-Fucosyltransferase (FUT8) Is the Sole Enzyme Responsible for the N-Acetylglucosaminyltransferase I-independent Core Fucosylation of High-mannose N-Glycans

Understanding the biosynthetic pathway of protein glycosylation in various expression cell lines is important for controlling and modulating the glycosylation profiles of recombinant glycoproteins. We found that expression of erythropoietin (EPO) in a HEK293S N-acetylglucosaminyltransferase I (GnT I...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Yang, Qiang, Wang, Lai-Xi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900256/
https://ncbi.nlm.nih.gov/pubmed/27008861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.720789
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