Ligand-Guided Selection of Target-Specific Aptamers: A Screening Technology for Identifying Specific Aptamers Against Cell-Surface Proteins

We report on a new strategy for identifying highly specific aptamers against a predetermined epitope of a target. Termed “ligand-guided selection” (LIGS), this method uniquely exploits the selection step, the core of SELEX (Systematic Evolution Exponential enrichment). LIGS uses a naturally occurrin...

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Detalles Bibliográficos
Publicado en:Nucleic Acid Ther
Main Authors: Zumrut, Hasan E., Ara, Mst Naznin, Fraile, Maria, Maio, George, Mallikaratchy, Prabodhika
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2016
Assuntos:
Brief Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900185/
https://ncbi.nlm.nih.gov/pubmed/27148897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2016.0611
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