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Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery
Large-scale genomic efforts to study human cancer, such as the cancer gene atlas (TCGA), have identified numerous cancer drivers in a wide variety of tumor types. However, there are limitations to this approach, the mutations and expression or copy number changes that are identified are not always c...
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| Veröffentlicht in: | Curr Opin Genet Dev |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4900178/ https://ncbi.nlm.nih.gov/pubmed/26051241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2015.04.007 |
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