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SHAPE Analysis of Long-Range Interactions Reveals Extensive and Thermodynamically Preferred Misfolding in a Fragile Group I Intron RNA()
Most functional RNAs require proteins to facilitate formation of their active structures. In the case of the yeast bI3 group I intron, splicing requires binding by two proteins, the intron-encoded bI3 maturase and the nuclear encoded Mrs1. Here, we use selective 2′-hydroxyl acylation analyzed by pri...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4900158/ https://ncbi.nlm.nih.gov/pubmed/18642882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800207b |
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