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Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicing

RNA is becoming an important therapeutic target. Many potential RNA targets require secondary or tertiary structure for function. Examples include ribosomal RNAs, RNase P RNAs, mRNAs with untranslated regions that regulate translation, and group I and group II introns. Here, a method is described to...

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Detalhes bibliográficos
Main Authors: Childs, Jessica L., Disney, Matthew D., Turner, Douglas H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123215/
https://ncbi.nlm.nih.gov/pubmed/12169671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172391199
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