Population genomics of drug resistance in Candida albicans

We followed adaptation in experimental microbial populations to inhibitory concentrations of an antimicrobial drug. The evolution of drug resistance was accompanied in all cases by changes in gene expression that persisted in the absence of the drug; the new patterns of gene expression were constitu...

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Main Authors: Cowen, Leah E., Nantel, André, Whiteway, Malcolm S., Thomas, David Y., Tessier, Daniel C., Kohn, Linda M., Anderson, James B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC123132/
https://ncbi.nlm.nih.gov/pubmed/12089321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102291099
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