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Self-splicing of a group I intron reveals partitioning of native and misfolded RNA populations in yeast

Stable RNAs must form specific three-dimensional structures, yet many RNAs become kinetically trapped in misfolded conformations. To understand the factors that control the accuracy of RNA folding in the cell, the self-splicing activity of the Tetrahymena group I intron was compared in different gen...

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Detalhes bibliográficos
Main Authors: Jackson, Scott A., Koduvayur, Sujatha, Woodson, Sarah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664722/
https://ncbi.nlm.nih.gov/pubmed/17135489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.184206
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