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Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication
Defects in mitochondrial oxidative phosphorylation have frequently been associated with Alzheimer's disease (AD), and both inherited and somatic mtDNA mutations have been reported in certain AD cases. To determine whether mtDNA mutations contribute more generally to the etiology of AD, we have...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC490002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15247418/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403649101 |
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