Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E

Toll-like receptors (TLRs) and the downstream adaptor molecule myeloid differentiation factor 88 (MyD88) play an essential role in the innate immune responses. Here, we demonstrate that genetic deficiency of TLR4 or MyD88 is associated with a significant reduction of aortic plaque areas in atheroscl...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Michelsen, Kathrin S., Wong, Michelle H., Shah, Prediman K., Zhang, Wenxuan, Yano, Juliana, Doherty, Terence M., Akira, Shizuo, Rajavashisth, Tripathi B., Arditi, Moshe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC489994/
https://ncbi.nlm.nih.gov/pubmed/15249654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403249101
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