The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

BACKGROUND: Resistance to taxane-based therapy in breast cancer patients is a major clinical problem that may be addressed through insight of the genomic alterations leading to taxane resistance in breast cancer cells. In the current study we used whole exome sequencing to discover somatic genomic a...

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Библиографические подробности
Опубликовано в: :BMC Genomics
Главные авторы: Hansen, Stine Ninel, Ehlers, Natasja Spring, Zhu, Shida, Thomsen, Mathilde Borg Houlberg, Nielsen, Rikke Linnemann, Liu, Dongbing, Wang, Guangbiao, Hou, Yong, Zhang, Xiuqing, Xu, Xun, Bolund, Lars, Yang, Huanming, Wang, Jun, Moreira, Jose, Ditzel, Henrik J, Brünner, Nils, Schrohl, Anne-Sofie, Stenvang, Jan, Gupta, Ramneek
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899892/
https://ncbi.nlm.nih.gov/pubmed/27277198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2749-4
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