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The stepwise evolution of the exome during acquisition of docetaxel resistance in breast cancer cells

BACKGROUND: Resistance to taxane-based therapy in breast cancer patients is a major clinical problem that may be addressed through insight of the genomic alterations leading to taxane resistance in breast cancer cells. In the current study we used whole exome sequencing to discover somatic genomic a...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:BMC Genomics
Main Authors: Hansen, Stine Ninel, Ehlers, Natasja Spring, Zhu, Shida, Thomsen, Mathilde Borg Houlberg, Nielsen, Rikke Linnemann, Liu, Dongbing, Wang, Guangbiao, Hou, Yong, Zhang, Xiuqing, Xu, Xun, Bolund, Lars, Yang, Huanming, Wang, Jun, Moreira, Jose, Ditzel, Henrik J, Brünner, Nils, Schrohl, Anne-Sofie, Stenvang, Jan, Gupta, Ramneek
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899892/
https://ncbi.nlm.nih.gov/pubmed/27277198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2749-4
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